From Chicago: 
Exit 55 South at the Normal-Business 51 exit (Main Street).   The exit ramp will take you to a stoplight, where you will turn left (south) onto Main Street. Continue traveling south on Main Street. Go straight on Main Street to College Ave; turn left onto College. Go one block and turn right on University St. The main Metcalf entrance is halfway up the block on your right.

From Mt. Vernon: 57 North to I74 at Champaign/Urbana. I74 West to Bloomington where I74 and I55 combine. Continue on I74/I55 until they split.  Stay on I55 North until the Normal-Business 51 South Exit (Main Street). Continue traveling south on Main Street to College Ave; turn left onto College. Go one block and turn right on University St. The main Metcalf entrance is halfway up the block on your right.

From Peoria: I74 West to I55 North (exit to I55 is in the left lane). Exit I55 at the Normal-Business 51 South exit (Main Street). Continue traveling south on Main Street to College Ave; turn left onto College. Go one block and turn right on University St. The main Metcalf entrance is halfway up the block on your right.

From Springfield: I55 North. Exit I55 at the Normal-Business 51 south exit (Main Street). Continue traveling south on Main Street. Turn left onto College Avenue. Go one block and turn right on University St. The main Metcalf entrance is halfway up the block on your right.